anidulafungin vs caspofungin
PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.
Side-by-side comparison of anidulafungin and caspofungin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Eraxis
Cancidas
Eraxis is an antifungal medicine. It treats certain Candida infections in your body.
Caspofungin is an antifungal medicine. It fights fungal infections in your body.
Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis. It can be used in adults and children 1 month and older. Eraxis also treats esophageal candidiasis (a Candida infection in the esophagus) in adults. However, Eraxis may not work as well for esophageal candidiasis, and the infection may come back.
Caspofungin treats several types of fungal infections. It is used for presumed fungal infections in patients with fever and low white blood cell counts. Caspofungin also treats infections caused by Candida, such as infections in the blood, abdomen, and esophagus. It can also treat invasive aspergillosis when other medicines don't work or can't be tolerated.
Eraxis belongs to a class of drugs called echinocandins. It works by stopping the growth of the fungus Candida. It does this by blocking a key part of the fungal cell wall.
Caspofungin stops fungi from growing. It does this by blocking a key part of the fungal cell wall. This causes the fungal cells to die.
- • Low potassium levels
- • Nausea
- • Diarrhea
- • Vomiting
- • Fever
- • Diarrhea
- • Fever
- • Increased liver enzyme levels
- • Decreased potassium levels
- • Rash
- Multiple Organ Dysfunction Syndrome 171
- Septic Shock 127
- Sepsis 115
- Pneumonia 94
- Pyrexia 90
- Death 223
- Lung infection 200
- Fever 196
- Blood infection 193
- Severe blood infection leading to organ damage 175
Eraxis can cause liver problems. Your doctor should check your liver function while you are taking Eraxis. Allergic reactions, including shock, can happen. Tell your doctor right away if you have any signs of an allergic reaction, like rash, hives, flushing, itching, trouble breathing, or low blood pressure. Eraxis contains fructose. If you have hereditary fructose intolerance, you should not take Eraxis.
Caspofungin can cause serious allergic reactions, including anaphylaxis. If you have signs of an allergic reaction, stop taking caspofungin right away. Caspofungin can also affect your liver. Your doctor will monitor your liver function with blood tests.
Eraxis may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Eraxis passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking Eraxis.
Caspofungin may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if caspofungin passes into breast milk, so talk to your doctor about breastfeeding while taking this medicine.
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How to Read This anidulafungin vs caspofungin Comparison
anidulafungin is classified in the Echinocandin Antifungal drug class, while caspofungin sits within the Echinocandin Antifungal class. Because both drugs share the same classification, they are often considered interchangeable in theory, but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, anidulafungin has 597 submissions while caspofungin has 987. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for anidulafungin or caspofungin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.