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Two medicines, side by side

Abaloparatide vs atenolol

Abaloparatide is labeled for osteoporosis; atenolol for high blood pressure, angina and heart attack and coronary artery disease. Their labels share no use, so they are not alternatives to each other. Drugs@FDA records approvals of abaloparatide since 2017 and of atenolol since 1981. In FDA's classes, abaloparatide is a parathyroid hormone-related peptide analog and atenolol a beta-adrenergic blocker.

Check it at the source: the abaloparatide FDA label on DailyMed (effective August 11, 2026); the atenolol FDA label on DailyMed (effective September 18, 2025).

Highlights of the abaloparatide record

Abaloparatide (Tymlos) · label of August 11, 2026

Used for

From the label: indications

TYMLOS is a human parathyroid hormone related peptide [PTHrP(1-34)] analog indicated for the: Treatment of postmenopausal women with osteoporosis at high risk for fracture or patients who have failed or are intolerant to other available osteoporosis therapy. […]

On the market

Earliest approval on file
April 28, 2017
Generic labelers
none listed
Pharmacy cost
Not in the survey

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the atenolol record

Atenolol (Tenormin) · label of September 18, 2025

Used for

From the label: indications

Hypertension TENORMIN is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including atenolol. […]

On the market

Earliest approval on file
August 19, 1981
Generic labelers
35 labelers
Pharmacy cost
$0.0217 per tablet

Supply and safety

Shortage
No current entry
Recalls
4

Source: FDA drug labels via openFDA (Abaloparatide label of August 11, 2026, Atenolol label of September 18, 2025); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do abaloparatide and atenolol differ on the record?

In FDA's classes, abaloparatide is a parathyroid hormone-related peptide analog and atenolol a beta-adrenergic blocker.

Generics: abaloparatide none approved; atenolol since 1988 (Drugs@FDA).

AbaloparatideAtenolol
Labeled forOsteoporosisHigh blood pressure, Angina, Heart attack and coronary artery disease
Pharmacologic classParathyroid Hormone-Related Peptide Analogbeta-Adrenergic Blocker
How it works (label)Abaloparatide is a PTHrP(1-34) analog which acts as an agonist at the PTH1 receptor (PTH1R). This results in activation of the cAMP signaling pathway in target cells.n/a
Half-life (label)n/aThe elimination half-life of oral TENORMIN is approximately 6 to 7 hours, and there is no alteration of the kinetic profile of the drug by chronic administration.
Earliest approval on file (Drugs@FDA)April 28, 2017August 19, 1981
First generic approvednoneJuly 15, 1988
Generic labelers (NDC)none listed35 labelers
Pharmacy cost (NADAC, each one's most listed form; strengths differ)n/a$0.0217 per tablet (Atenolol 25 mg tablet)
12-month price changen/a-3%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded04
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)29,258132,491
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to abaloparatide
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