FDA pharmacologic class
Tetracyclines
3 medicines are in FDA's class of tetracycline-class drugs (tetracyclines): doxycycline (Oracea), minocycline (Minocin) and sarecycline (Seysara). 2 of the 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is doxycycline hyclate 100 mg tablet at $0.118 per tablet (NADAC).
Which medicines are tetracyclines?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Doxycycline | Oracea, Acticlate, Doryx | 83 labelers | $0.118 per tablet 100 mg tablet | No | A presentation being discontinued | 19 |
| Minocycline | Emrosi, Amzeeq, Zilxi | 21 labelers | $0.343 per capsule 100 mg capsule | No | No current entry | 3 |
| Sarecycline | Seysara | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price