FDA pharmacologic class
SGLT2 inhibitors
5 medicines are in FDA's class of sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors): dapagliflozin (Farxiga), empagliflozin (Jardiance), canagliflozin (Invokana), bexagliflozin (Brenzavvy) and sotagliflozin (Inpefa); 6 combination products also contain one. 3 of the 11 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is dapagliflozin 10 mg tablet at $0.184 per tablet (NADAC).
Which medicines are sglt2 inhibitors?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Dapagliflozin | Farxiga | 22 labelers | $0.184 per tablet 10 mg tablet | No | No current entry | 0 |
| Dapagliflozin and metformin | Xigduo | 8 labelers | $0.720 per tablet 10-1,000 mg tablet | Yes | No current entry | 2 |
| Empagliflozin | Jardiance | none listed | $11.19 per tablet 10 mg tablet | No | No current entry | 2 |
| Canagliflozin and metformin | Invokamet | none listed | $9.58 per tablet 150-1,000 mg tablet | Yes | No current entry | 1 |
| Empagliflozin and metformin | Synjardy | none listed | $5.60 per tablet 12.5-1,000 mg tablet | Yes | No current entry | 4 |
| Canagliflozin | Invokana | none listed | $19.13 per tablet 100 mg tablet | No | No current entry | 0 |
| Empagliflozin and linagliptin and metformin | Trijardy | none listed | $11.28 per tablet 10-5-1,000 mg tablet | Yes | No current entry | 0 |
| Bexagliflozin | Brenzavvy | none listed | n/a | No | No current entry | 0 |
| Empagliflozin and linagliptin | Glyxambi | none listed | $11.24 per tablet 10 mg-5 mg tablet | No | No current entry | 1 |
| Sotagliflozin | Inpefa | none listed | $20.37 per tablet 200 mg tablet | No | No current entry | 0 |
| Dapagliflozin and saxagliptin | none listed | 1 labeler | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price