FDA pharmacologic class

Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

5 medicines are in FDA's class of hepatitis b virus nucleoside analog reverse transcriptase inhibitors: entecavir (Baraclude), lamivudine (Epivir), tenofovir disoproxil (Viread), adefovir dipivoxil and tenofovir alafenamide (Vemlidy); 17 combination products also contain one. 11 of the 22 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is entecavir 0.5 mg tablet at $0.219 per tablet (NADAC).

Which medicines are hepatitis b virus nucleoside analog reverse transcriptase inhibitor?

Recalls: FDA enforcement reports, 2012 on
Medicine	Brand names	Generic labelers (all forms)	Pharmacy cost	Boxed warning	Shortage	Recalls since 2012
Emtricitabine and tenofovir disoproxil	Truvada	25 labelers	$0.529 per tablet 200-300 mg tablet	Yes	No current entry	1
Entecavir	Baraclude	15 labelers	$0.219 per tablet 0.5 mg tablet	Yes	No current entry	5
Lamivudine	Epivir	14 labelers	$0.489 per tablet 150 mg tablet	Yes	No current entry	2
Tenofovir disoproxil	Viread	15 labelers	$0.294 per tablet 300 mg tablet	Yes	No current entry	0
Lamivudine and zidovudine	Combivir	7 labelers	$0.771 per tablet Lamivudine-zidovudine tablet	Yes	No current entry	1
Efavirenz and emtricitabine and tenofovir disoproxil	none listed	7 labelers	$1.12 per tablet 600-200-300 mg tablet	Yes	No current entry	0
Abacavir and lamivudine	none listed	6 labelers	$1.48 per unit 600-300 mg	Yes	No current entry	0
Bictegravir and emtricitabine and tenofovir alafenamide	Biktarvy	none listed	$136.73 per tablet 50-200-25 mg tablet	Yes	No current entry	0
Efavirenz and lamivudine and tenofovir disoproxil	Symfi	1 labeler	n/a	Yes	No current entry	0
Emtricitabine and rilpivirine and tenofovir disoproxil	Complera	2 labelers	$114.50 per tablet 200-25-300 mg tablet	Yes	No current entry	0
Abacavir and dolutegravir and lamivudine	Triumeq	none listed	$130.01 per tablet 600-50-300 mg tablet	Yes	No current entry	1
Adefovir dipivoxil	none listed	2 labelers	$21.73 per tablet 10 mg tablet	Yes	No current entry	0
Emtricitabine and tenofovir alafenamide	Descovy	none listed	$74.94 per tablet 200-25 mg tablet	Yes	No current entry	0
Abacavir and lamivudine and zidovudine	none listed	1 labeler	n/a	Yes	No current entry	0
Cobicistat, darunavir, emtricitabine and tenofovir alafenamide	Symtuza	none listed	$152.87 per tablet 800-150-200-10 mg tablet	Yes	No current entry	0
Cobicistat, elvitegravir, emtricitabine and tenofovir alafenamide	Genvoya	none listed	$143.35 per tablet Genvoya tablet	Yes	No current entry	0
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil	Stribild	none listed	$150.14 per tablet Stribild tablet	Yes	No current entry	0
Dolutegravir and lamivudine	Dovato	none listed	$105.22 per tablet 50-300 mg tablet	Yes	No current entry	0
Doravirine and lamivudine and tenofovir disoproxil	Delstrigo	none listed	$93.06 per tablet 100-300-300 mg tablet	Yes	No current entry	0
Emtricitabine and rilpivirine and tenofovir alafenamide	Odefsey	none listed	$130.49 per tablet Odefsey tablet	Yes	No current entry	0
Lamivudine and tenofovir disoproxil	Cimduo	none listed	n/a	Yes	No current entry	0
Tenofovir alafenamide	Vemlidy	none listed	$51.98 per tablet 25 mg tablet	Yes	No current entry	0

Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)

What do pharmacies pay?

Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.

Entecavir$0.219
Tenofovir disoproxil$0.294
Lamivudine$0.489
Emtricitabine and tenofovir disoproxil$0.529
Lamivudine and zidovudine$0.771
Efavirenz and emtricitabine and tenofovir disoproxil$1.12
Abacavir and lamivudine$1.48
Adefovir dipivoxil$21.73
Tenofovir alafenamide$51.98
Emtricitabine and tenofovir alafenamide$74.94
Doravirine and lamivudine and tenofovir disoproxil$93.06
Dolutegravir and lamivudine$105.22
Emtricitabine and rilpivirine and tenofovir disoproxil$114.50
Abacavir and dolutegravir and lamivudine$130.01
Emtricitabine and rilpivirine and tenofovir alafenamide$130.49
Bictegravir and emtricitabine and tenofovir alafenamide$136.73
Cobicistat, elvitegravir, emtricitabine and tenofovir alafenamide$143.35
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil$150.14
Cobicistat, darunavir, emtricitabine and tenofovir alafenamide$152.87

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Every drug class
Medicines A to Z