FDA pharmacologic class
Gonadotropin Releasing Hormone Receptor Agonist
4 medicines are in FDA's class of gonadotropin releasing hormone receptor agonists: leuprolide (Lupron), goserelin (Zoladex), histrelin (Supprelin) and nafarelin (Synarel). 1 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is leuprolide 2wk 14 mg/2.8 ml kt at $197.61 per unit (NADAC).
Which medicines are gonadotropin releasing hormone receptor agonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Leuprolide | Lupron, Eligard, Camcevi | 12 labelers | $197.61 per unit 2wk 14 mg/2.8 mL kt | No | No current entry | 6 |
| Goserelin | Zoladex | none listed | n/a | No | No current entry | 0 |
| Histrelin | Supprelin | none listed | n/a | No | No current entry | 0 |
| Nafarelin | Synarel | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price