FDA pharmacologic class
Carbonic Anhydrase Inhibitor
4 medicines are in FDA's class of carbonic anhydrase inhibitors: acetazolamide, dorzolamide, brinzolamide (Azopt) and dichlorphenamide (Keveyis); 2 combination products also contain one. 5 of the 6 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is acetazolamide 250 mg tablet at $0.134 per tablet (NADAC).
Which medicines are carbonic anhydrase inhibitor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Acetazolamide | none listed | 38 labelers | $0.134 per tablet 250 mg tablet | No | No current entry | 2 |
| Dorzolamide and timolol | Cosopt | 14 labelers | $0.893 per mL Dorzolamide-timolol eye drops | No | No current entry | 1 |
| Dorzolamide | none listed | 14 labelers | $0.835 per mL 2% eye drops | No | No current entry | 0 |
| Brinzolamide | Azopt | 4 labelers | $9.00 per mL 1% eye drops | No | No current entry | 1 |
| Dichlorphenamide | Keveyis, Ormalvi | 3 labelers | n/a | No | No current entry | 0 |
| Brimonidine and brinzolamide | Simbrinza | none listed | $26.04 per mL 1%-0.2% eye drop | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price