Medicines labeled for the same conditions
Alternatives to zaleplon
11 other medicines are given the same way (oral) and in the same FDA class as zaleplon or labeled mainly for the same use (insomnia); the others include 5 benzodiazepines, 3 orexin receptor antagonists and 1 gamma-aminobutyric acid a receptor positive modulator (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as zaleplon?
Insomnia lists all 14 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Zaleplongamma-aminobutyric acid a receptor agonist | this medicine | 9 labelers | $0.141 per capsule 10 mg capsule | Yes | No current entry |
| Zolpidemgamma-aminobutyric acid a receptor positive modulator | Insomnia | 39 labelers | $0.0344 per tablet 5 mg tablet | Yes | No current entry |
| Eszopiclone | Insomnia | 26 labelers | $0.0993 per tablet 1 mg tablet | Yes | No current entry |
| Temazepambenzodiazepine | Insomnia | 20 labelers | $0.0767 per capsule 15 mg capsule | Yes | No current entry |
| Ramelteonmelatonin receptor agonist | Insomnia | 27 labelers | $0.660 per tablet 8 mg tablet | No | A presentation being discontinued |
| Triazolambenzodiazepine | Insomnia | 7 labelers | $0.308 per tablet 0.25 mg tablet | Yes | No current entry |
| Estazolambenzodiazepine | Insomnia | 3 labelers | $0.839 per tablet 2 mg tablet | Yes | No current entry |
| Suvorexantorexin receptor antagonist | Insomnia | none listed | $15.21 per tablet 10 mg tablet | No | No current entry |
| Daridorexantorexin receptor antagonist | Insomnia | none listed | $16.70 per tablet 25 mg tablet | No | No current entry |
| Flurazepambenzodiazepine | Insomnia | 1 labeler | n/a | Yes | In shortage |
| Lemborexantorexin receptor antagonist | Insomnia | none listed | $11.57 per tablet 10 mg tablet | No | No current entry |
| Quazepambenzodiazepine | Insomnia | none listed | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Zaleplon: the full record
- label, generics, price, shortages, recalls
- Zaleplon vs zolpidem
- two records side by side
- Zaleplon vs eszopiclone
- two records side by side
- Ramelteon vs zaleplon
- two records side by side