Alternatives to paroxetine
5 same-class SPL records vs paroxetine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Paxil
About paroxetine
Paroxetine (Paxil) is a medicine that can help treat depression and anxiety disorders. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs).
Used for: Paroxetine is used to treat several conditions in adults. These include major depressive disorder (MDD), obsessive compulsive disorder (OCD), panic disorder (PD), social anxiety disorder (SAD), generalized anxiety disorder (GAD), and posttraumatic stress disorder (PTSD). It helps to improve mood and reduce anxiety and panic feelings.
5 Selective Serotonin Reuptake Inhibitor (SSRI) peers (wide set)
citalopram
RxCelexa
Citalopram is used to treat major depressive disorder (MDD) in adults. Depression can cause feelings of sadness, loss of interest, and difficulty functioning in daily life. This medicine can help improve your mood and overall well-being.
escitalopram
RxLexapro
Escitalopram is used to treat major depressive disorder (MDD) in adults and children 12 years and older. It also treats generalized anxiety disorder (GAD) in adults. This medicine can help improve your mood and reduce feelings of worry.
fluoxetine
RxProzac, Sarafem
Fluoxetine can treat major depressive disorder in adults and children. It also treats obsessive-compulsive disorder (OCD) in adults and children. Fluoxetine can help with bulimia nervosa (an eating disorder) and panic disorder. Sometimes, it is used with another medicine called olanzapine to treat depression related to bipolar disorder.
fluvoxamine
RxLuvox
Fluvoxamine is used to treat obsessive compulsive disorder (OCD). OCD involves having constant, unwanted thoughts or behaviors that you feel the need to repeat. These thoughts or actions can cause you distress and interfere with your daily life.
sertraline
RxZoloft
Sertraline is used to treat major depressive disorder in adults. This means it can help with ongoing sadness or loss of interest in things. It also treats obsessive-compulsive disorder (OCD), where you have unwanted thoughts or behaviors that you can't control. Sertraline can also treat panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder.
paroxetine vs citalopram & escitalopram · FAERS reaction fields
FAERS top-reaction field "Nausea" shows the widest count spread between paroxetine and citalopram, escitalopram, fluoxetine in this extract (7,426-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | paroxetine | citalopram | escitalopram | fluoxetine |
|---|---|---|---|---|
| Drug Interaction | 1,825 | 4,348 | 3,707 | 3,335 |
| Fatigue | 1,821 | 8,930 | 9,196 | 3,156 |
| Nausea | 1,738 | 8,210 | 9,164 | 3,233 |
| Toxicity To Various Agents | 1,579 | 5,061 | - | 3,316 |
| Anxiety | 1,476 | 5,436 | 6,447 | 2,444 |
| Diarrhoea | 1,453 | 6,218 | 6,709 | 2,374 |
| Headache | 1,446 | 6,656 | 7,114 | 2,774 |
| Dizziness | 1,363 | 5,705 | 6,087 | 2,357 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
paroxetine peer mix vs class inventory
Peer mix
0 OTC and 5 Rx SPL records in this peer set (5 total). Class inventory for Selective Serotonin Reuptake Inhibitor (SSRI): 6 drugs.
Frequently Asked Questions
What same-class SPL records sit beside paroxetine? ▼
Reading a wide Selective Serotonin Reuptake Inhibitor (SSRI) peer set (5 records)
paroxetine (Paxil) sits in a wide Selective Serotonin Reuptake Inhibitor (SSRI) peer set (5 of 5 class peers shown). Labeled indication field for paroxetine: Paroxetine is used to treat several conditions in adults.
Top FAERS reaction fields for paroxetine total 15,250 reports across 10 reactions, set beside citalopram, escitalopram, fluoxetine. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for paroxetine: see also the generic vs brand label guide when reading Paxil SPL strings.
Read our methodology - how this data is sourced, computed, and verified.