Medicines labeled for the same conditions
Alternatives to naproxen and sumatriptan
13 other medicines are given the same way (oral) and in the same FDA class as naproxen and sumatriptan or labeled mainly for the same use (migraine); 9 are in its class, serotonin-1b and serotonin-1d receptor agonists: celecoxib, diclofenac, rizatriptan, zolmitriptan and 5 more; the others include 3 calcitonin gene-related peptide receptor antagonists (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0619 per diclofenac sod DR 75 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as naproxen and sumatriptan?
Migraine lists all 27 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Naproxen and sumatriptanserotonin-1b and serotonin-1d receptor agonist | this medicine | 3 labelers | $10.46 per unit 85-500 mg | Yes | No current entry |
| Celecoxibnonsteroidal anti-inflammatory drug · same class | Migraine | 65 labelers | $0.0762 per capsule 200 mg capsule | Yes | No current entry |
| Diclofenacnonsteroidal anti-inflammatory drug · same class | Migraine | 67 labelers | $0.0619 per tablet 75 mg tablet | Yes | A presentation being discontinued |
| Rizatriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 25 labelers | $0.335 per tablet 10 mg tablet | No | No current entry |
| Zolmitriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 18 labelers | $1.02 per tablet 2.5 mg tablet | No | No current entry |
| Eletriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 10 labelers | $1.75 per tablet 40 mg tablet | No | No current entry |
| Naratriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 4 labelers | $1.08 per tablet 2.5 mg tablet | No | No current entry |
| Almotriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 3 labelers | $16.86 per tablet 12.5 mg tablet | No | No current entry |
| Frovatriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | 4 labelers | $2.72 per tablet 2.5 mg tablet | No | A presentation being discontinued |
| Meloxicam and rizatriptanserotonin-1b and serotonin-1d receptor agonist · same class | Migraine | none listed | $122.64 per tablet 20-10 mg tablet | Yes | No current entry |
| Ubrogepantcalcitonin gene-related peptide receptor antagonist | Migraine | none listed | $109.11 per tablet 100 mg tablet | No | No current entry |
| Atogepantcalcitonin gene-related peptide receptor antagonist | Migraine | none listed | $38.36 per tablet 10 mg tablet | No | No current entry |
| Rimegepantcalcitonin gene-related peptide receptor antagonist | Migraine | none listed | $128.67 per tablet 75 mg tablet | No | No current entry |
| Lasmiditan | Migraine | none listed | $88.77 per tablet 100 mg tablet | No | A presentation being discontinued |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Naproxen and sumatriptan: the full record
- label, generics, price, shortages, recalls