Skip to main content

Medicines labeled for the same conditions

Alternatives to levorphanol

36 other medicines are given the same way (oral) and in the same FDA class as levorphanol or labeled mainly for the same use (pain); 19 are in its class, opioid agonists: acetaminophen and hydrocodone, oxycodone, acetaminophen and oxycodone, tramadol and 15 more; the others include 6 nonsteroidal anti-inflammatory drugs, 1 cyclooxygenase inhibitor and 1 cholinergic muscarinic antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0248 per tramadol HCl 50 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as levorphanol?

The first 24 of the 36, the same class first. Pain lists all 80 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Levorphanolopioid agonistthis medicine7 labelers$10.65 per tablet 2 mg tabletYesNo current entry
Acetaminophen and hydrocodoneopioid agonist · same classPain38 labelers$0.152 per tablet 10-325 mg tabletYesNo current entry
Oxycodoneopioid agonist · same classPain34 labelers$0.0884 per tablet 5 mg tabletYesNo current entry
Acetaminophen and oxycodoneopioid agonist · same classPain30 labelers$0.183 per tablet 7.5-325 mg tabletYesA presentation being discontinued
Tramadolopioid agonist · same classPain40 labelers$0.0248 per tablet 50 mg tabletYesNo current entry
Morphineopioid agonist · same classPain17 labelers$0.226 per tablet 15 mg tabletYesIn shortage
Acetaminophen and codeineopioid agonist · same classPain25 labelers$0.256 per tablet 3 tabletYesNo current entry
Hydromorphoneopioid agonist · same classPain11 labelers$0.219 per tablet 4 mg tabletYesIn shortage
Methadoneopioid agonist · same classPain17 labelers$0.177 per tablet 10 mg tabletYesNo current entry
Oxymorphoneopioid agonist · same classPain9 labelersn/aYesNo current entry
Tapentadolopioid agonist · same classPain4 labelers$14.48 per tablet 100 mg tabletYesNo current entry
Hydrocodoneopioid agonist · same classPain1 labeler$7.95 per capsule 15 mg capsuleYesNo current entry
Acetaminophen and tramadolopioid agonist · same classPain12 labelers$0.116 per tablet 37.5-325 mg tabletYesNo current entry
Acetaminophen, butalbital, caffeine and codeinebarbiturate · same classPain5 labelers$0.798 per capsule 50-325-40-30 mg capsuleYesNo current entry
Codeineopioid agonist · same classPain1 labeler$0.726 per tablet 30 mg tabletYesNo current entry
Hydrocodone and ibuprofenopioid agonist · same classPain2 labelers$0.487 per unit 7.5-200YesNo current entry
Aspirin, butalbital, caffeine and codeinebarbiturate · same classPain4 labelers$1.00 per capsule Ascomp with codeine capsuleYesNo current entry
Meperidineopioid agonist · same classPain3 labelers$0.157 per mL 50 mg/5 mL solutionYesListed; available
Acetaminophen and caffeine and dihydrocodeinemethylxanthine · same classPain1 labelern/aYesNo current entry
Aspirin and oxycodoneplatelet aggregation inhibitor · same classPain1 labelern/aYesNo current entry
AspirinPainnone listed$0.0142 per tablet 81 mg tabletNoA presentation being discontinued
Diclofenacnonsteroidal anti-inflammatory drugPain67 labelers$0.0619 per tablet 75 mg tabletYesA presentation being discontinued
PhenazopyridinePainnone listed$0.154 per tablet 100 mg tabletNoNo current entry
Etodolacnonsteroidal anti-inflammatory drugPain30 labelers$0.262 per tablet 400 mg tabletYesNo current entry
Acetaminophen and ibuprofennonsteroidal anti-inflammatory drugPain51 labelers$0.107 per unit 250-125 mgYesNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Levorphanol: the full record
label, generics, price, shortages, recalls
Levorphanol vs oxycodone
two records side by side
Levorphanol vs morphine
two records side by side
Levorphanol vs oxymorphone
two records side by side