Alternatives to fexofenadine
4 same-class SPL records vs fexofenadine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Allegra
About fexofenadine
Fexofenadine (Allegra) is an antihistamine medicine. It helps reduce hives and relieve itching.
Used for: This medicine treats hives and itching caused by hives. It will not stop hives or allergic skin reactions from happening. Talk to your doctor if you have questions about your condition.
4 Second-Generation Antihistamine peers (wide set)
cetirizine
OTCZyrtec
This medicine treats allergy symptoms. It can help with a runny nose, sneezing, and itchy, watery eyes. It also helps with itching of the nose or throat caused by hay fever or other upper respiratory allergies.
desloratadine
RxClarinex
This medicine treats allergy symptoms. It can help with seasonal allergies like hay fever. It also treats year-round allergies and chronic hives by reducing itching and the number and size of hives.
levocetirizine
OTCXyzal
This medicine treats allergy symptoms. It can help with a runny nose, sneezing, and itchy, watery eyes. It also helps with itching of the nose or throat caused by hay fever or other allergies.
loratadine
OTCClaritin
This medicine treats allergy symptoms. It can help with a runny nose, itchy and watery eyes, and sneezing. It also helps with itching of the nose or throat caused by hay fever or other upper respiratory allergies.
fexofenadine vs cetirizine & desloratadine · FAERS reaction fields
FAERS top-reaction field "Fatigue" shows the widest count spread between fexofenadine and cetirizine, desloratadine, levocetirizine in this extract (12,003-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | fexofenadine | cetirizine | desloratadine | levocetirizine |
|---|---|---|---|---|
| Headache | 878 | 7,470 | 465 | - |
| Fatigue | 858 | 12,861 | 601 | - |
| Nausea | 778 | - | 582 | - |
| Pruritus | 765 | 7,514 | 422 | - |
| Extra Dose Administered | 700 | - | - | - |
| Diarrhoea | 693 | - | 448 | - |
| Dizziness | 648 | - | 439 | - |
| Rash | 605 | 9,771 | 374 | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
fexofenadine peer mix vs class inventory
Peer mix
3 OTC and 1 Rx SPL records in this peer set (4 total). Class inventory for Second-Generation Antihistamine: 5 drugs.
Frequently Asked Questions
How many OTC vs Rx SPL records sit beside fexofenadine? ▼
Reading a wide Second-Generation Antihistamine peer set (4 records)
fexofenadine (Allegra) sits in a wide Second-Generation Antihistamine peer set (4 of 4 class peers shown). Labeled indication field for fexofenadine: This medicine treats hives and itching caused by hives.
Top FAERS reaction fields for fexofenadine total 7,111 reports across 10 reactions, set beside cetirizine, desloratadine, levocetirizine. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for fexofenadine: see also the generic vs brand label guide when reading Allegra SPL strings.
Read our methodology - how this data is sourced, computed, and verified.