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Medicines labeled for the same conditions

Alternatives to ertugliflozin and sitagliptin

29 other medicines are given the same way (oral) and in the same FDA class as ertugliflozin and sitagliptin or labeled mainly for the same use (type 2 diabetes); 9 are in its class, dipeptidyl peptidase 4 inhibitors: alogliptin, alogliptin and pioglitazone, linagliptin and metformin, metformin and saxagliptin and 5 more; the others include 5 sulfonylureas, 5 sodium-glucose cotransporter 2 inhibitors and 3 peroxisome proliferator receptor gamma agonists (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $1.04 per saxagliptin HCl 5 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as ertugliflozin and sitagliptin?

The first 24 of the 29, the same class first. Type 2 diabetes lists all 52 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Ertugliflozin and sitagliptindipeptidyl peptidase 4 inhibitorthis medicinenone listed$17.59 per tablet 15-100 mg tabletNoNo current entry
Alogliptindipeptidyl peptidase 4 inhibitor · same classType 2 diabetesnone listed$4.96 per tablet 12.5 mg tabletNoNo current entry
Alogliptin and pioglitazoneperoxisome proliferator receptor gamma agonist · same classType 2 diabetesnone listed$4.73 per tablet 25-15 mg tabletYesNo current entry
Linagliptin and metformindipeptidyl peptidase 4 inhibitor · same classType 2 diabetes1 labeler$8.44 per tablet 2.5 mg-1,000 mg tabletYesNo current entry
Metformin and saxagliptindipeptidyl peptidase 4 inhibitor · same classType 2 diabetes2 labelers$9.65 per tablet 5-1,000 mg tabletYesNo current entry
Saxagliptindipeptidyl peptidase 4 inhibitor · same classType 2 diabetes3 labelers$1.04 per tablet 5 mg tabletNoNo current entry
Alogliptin and metformindipeptidyl peptidase 4 inhibitor · same classType 2 diabetesnone listed$2.46 per unit 12.5-1000YesNo current entry
Empagliflozin and linagliptin and metforminsodium-glucose cotransporter 2 inhibitor · same classType 2 diabetesnone listed$11.28 per tablet 10-5-1,000 mg tabletYesNo current entry
Linagliptindipeptidyl peptidase 4 inhibitor · same classType 2 diabetesnone listed$16.80 per tablet 5 mg tabletNoNo current entry
Empagliflozin and linagliptinsodium-glucose cotransporter 2 inhibitor · same classType 2 diabetesnone listed$11.24 per tablet 10 mg-5 mg tabletNoNo current entry
MetforminbiguanideType 2 diabetes83 labelers$0.0145 per tablet 500 mg tabletYesNo current entry
GlipizidesulfonylureaType 2 diabetes31 labelers$0.0339 per tablet 5 mg tabletNoNo current entry
GlimepiridesulfonylureaType 2 diabetes29 labelers$0.0507 per tablet 4 mg tabletNoNo current entry
Pioglitazoneperoxisome proliferator receptor gamma agonistType 2 diabetes22 labelers$0.0675 per tablet 15 mg tabletYesNo current entry
GlyburidesulfonylureaType 2 diabetes16 labelers$0.0643 per tablet 5 mg tabletNoA presentation being discontinued
Dapagliflozin and metforminsodium-glucose cotransporter 2 inhibitorType 2 diabetes8 labelers$0.720 per tablet 10-1,000 mg tabletYesNo current entry
Glyburide and metforminsulfonylureaType 2 diabetes11 labelers$0.171 per unit 2.5-500 mgYesNo current entry
Glipizide and metforminsulfonylureaType 2 diabetes9 labelers$0.242 per unit 2.5-250 mgNoNo current entry
RepaglinideglinideType 2 diabetes7 labelers$0.0987 per tablet 1 mg tabletNoNo current entry
NateglinideglinideType 2 diabetes9 labelers$0.179 per tablet 60 mg tabletNoNo current entry
Acarbosealpha-glucosidase inhibitorType 2 diabetes6 labelers$0.274 per tablet 100 mg tabletNoNo current entry
Metformin and pioglitazoneperoxisome proliferator receptor gamma agonistType 2 diabetes5 labelers$0.283 per unit 15-500YesNo current entry
SemaglutideGLP-1 receptor agonistType 2 diabetesnone listed$33.13 per tablet 1.5 mg tabletYesA presentation being discontinued
Canagliflozin and metforminsodium-glucose cotransporter 2 inhibitorType 2 diabetesnone listed$9.58 per tablet 150-1,000 mg tabletYesNo current entry
Empagliflozin and metforminsodium-glucose cotransporter 2 inhibitorType 2 diabetesnone listed$5.60 per tablet 12.5-1,000 mg tabletYesNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Ertugliflozin and sitagliptin: the full record
label, generics, price, shortages, recalls