Medicines labeled for the same conditions
Alternatives to daridorexant
11 other medicines are given the same way (oral) and in the same FDA class as daridorexant or labeled mainly for the same use (insomnia); 2 are in its class, orexin receptor antagonists: suvorexant and lemborexant; the others include 5 benzodiazepines, 1 gamma-aminobutyric acid a receptor positive modulator and 1 melatonin receptor agonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $11.57 per Dayvigo 10 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as daridorexant?
Insomnia lists all 14 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Daridorexantorexin receptor antagonist | this medicine | none listed | $16.70 per tablet 25 mg tablet | No | No current entry |
| Suvorexantorexin receptor antagonist · same class | Insomnia | none listed | $15.21 per tablet 10 mg tablet | No | No current entry |
| Lemborexantorexin receptor antagonist · same class | Insomnia | none listed | $11.57 per tablet 10 mg tablet | No | No current entry |
| Zolpidemgamma-aminobutyric acid a receptor positive modulator | Insomnia | 39 labelers | $0.0344 per tablet 5 mg tablet | Yes | No current entry |
| Eszopiclone | Insomnia | 26 labelers | $0.0993 per tablet 1 mg tablet | Yes | No current entry |
| Temazepambenzodiazepine | Insomnia | 20 labelers | $0.0767 per capsule 15 mg capsule | Yes | No current entry |
| Ramelteonmelatonin receptor agonist | Insomnia | 27 labelers | $0.660 per tablet 8 mg tablet | No | A presentation being discontinued |
| Zaleplongamma-aminobutyric acid a receptor agonist | Insomnia | 9 labelers | $0.141 per capsule 10 mg capsule | Yes | No current entry |
| Triazolambenzodiazepine | Insomnia | 7 labelers | $0.308 per tablet 0.25 mg tablet | Yes | No current entry |
| Estazolambenzodiazepine | Insomnia | 3 labelers | $0.839 per tablet 2 mg tablet | Yes | No current entry |
| Flurazepambenzodiazepine | Insomnia | 1 labeler | n/a | Yes | In shortage |
| Quazepambenzodiazepine | Insomnia | none listed | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Daridorexant: the full record
- label, generics, price, shortages, recalls