Medicines labeled for the same conditions
Alternatives to chlorpheniramine and ibuprofen and phenylephrine
14 other medicines are given the same way (oral) and in the same FDA class as chlorpheniramine and ibuprofen and phenylephrine or labeled mainly for the same use (allergies); 11 are in its class, alpha-1 adrenergic agonists: diphenhydramine, naproxen, cetirizine, fexofenadine and 7 more; the others include 1 expectorant and 1 kinase inhibitor (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0185 per mL (Child allergy rlf 12.5 mg/5 mL) (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as chlorpheniramine and ibuprofen and phenylephrine?
Allergies lists all 36 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Chlorpheniramine and ibuprofen and phenylephrinealpha-1 adrenergic agonist | this medicine | none listed | n/a | No | No current entry |
| Diphenhydraminehistamine-1 receptor antagonist · same class | Allergies, Cough and cold | 4 labelers | $0.0185 per mL 12.5 mg/5 mL | No | No current entry |
| Naproxennonsteroidal anti-inflammatory drug · same class | Cough and cold | 146 labelers | $0.0565 per tablet 500 mg tablet | Yes | No current entry |
| Cetirizinehistamine-1 receptor antagonist · same class | Allergies | 164 labelers | $0.0613 per tablet 10 mg tablet | No | No current entry |
| Fexofenadinehistamine-1 receptor antagonist · same class | Allergies | 110 labelers | $0.230 per tablet 180 mg tablet | No | No current entry |
| Acetaminophen and aspirin and caffeineplatelet aggregation inhibitor · same class | Cough and cold | 39 labelers | $0.0648 per unit 250-250-65 mg cplt | No | No current entry |
| Levocetirizinehistamine-1 receptor antagonist · same class | Allergies | 53 labelers | $0.0511 per tablet 5 mg tablet | No | No current entry |
| Fexofenadine and pseudoephedrinehistamine-1 receptor antagonist · same class | Cough and cold | 27 labelers | $0.483 per tablet 60-120 tablet | No | No current entry |
| Desloratadinehistamine-1 receptor antagonist · same class | Allergies | 9 labelers | $0.258 per tablet 5 mg tablet | No | No current entry |
| Naproxen and pseudoephedrinealpha-adrenergic agonist · same class | Cough and cold | 10 labelers | $0.244 per unit 220-120 mg | No | No current entry |
| Carbinoxaminehistamine-1 receptor antagonist · same class | Allergies | 7 labelers | $0.398 per tablet 4 mg tablet | No | No current entry |
| Desloratadine and pseudoephedrinehistamine-1 receptor antagonist · same class | Allergies | none listed | $6.07 per tablet 12 hr 2.5-120 mg tablet | No | No current entry |
| Guaifenesin and pseudoephedrineexpectorant | Allergies, Cough and cold | 30 labelers | $0.384 per unit 600-60 mg | No | No current entry |
| Clemastine | Allergies | 3 labelers | $3.18 per tablet 2.68 mg tablet | No | No current entry |
| Remibrutinibkinase inhibitor | Allergies | none listed | $72.46 per tablet 25 mg tablet | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Chlorpheniramine and ibuprofen and phenylephrine: the full record
- label, generics, price, shortages, recalls