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Medicines labeled for the same conditions

Alternatives to benzoyl peroxide

9 other medicines are given the same way (topical) and in the same FDA class as benzoyl peroxide or labeled mainly for the same use (acne); the others include 3 retinoids, 1 sulfone and 1 lincosamide antibacterial (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as benzoyl peroxide?

Acne lists all 26 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (topical)Pharmacy costBoxed warningShortage
Benzoyl peroxidethis medicinenone listed$0.0469 per gram 10% washNoNo current entry
Salicylic acidAcnenone listed$0.102 per patch Callus removers patchNoNo current entry
SulfurAcnenone listedn/aNoNo current entry
TretinoinretinoidAcne19 labelers$0.506 per gram 0.025% creamNoNo current entry
AdapaleneretinoidAcne34 labelers$0.504 per gram 0.3% gelNoNo current entry
DapsonesulfoneAcne16 labelers$0.664 per gram 5% gelNoA presentation being discontinued
Azelaic acidAcne5 labelers$0.441 per gram 15% gelNoNo current entry
Clindamycin and tretinoinlincosamide antibacterialAcne3 labelers$3.91 per gram 1.2%-0.025%NoNo current entry
Clascoteroneandrogen receptor inhibitorAcnenone listed$10.00 per gram 1% creamNoNo current entry
TrifaroteneretinoidAcnenone listed$16.36 per gram 0.005% creamNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

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Adapalene vs benzoyl peroxide
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