FDA Drug Shortage Database
Promethazine (Phenergan) shortage
The FDA Drug Shortage Database lists 7 of 10 promethazine presentations as limited or unavailable (updated September 22, 2026); the first entry was posted on November 21, 2023. 3 more presentations are on the list as available.
- Generic listed
- In shortage
Check it at the source: the FDA Drug Shortage Database.
Which strengths are short?
| Strength | Limited or unavailable now | Listed now, available | Resolved or discontinued |
|---|---|---|---|
| 25mg/1ml injection | 3 | 2 | 0 |
| 50mg/1ml injection | 3 | 2 | 0 |
Which presentations are listed?
Limited or unavailable now (6)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Unavailable; Other |
| Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Unavailable; Other |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Unavailable |
| Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Unavailable; Other |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Unavailable; Demand increase for the drug |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Limited Availability; Demand increase for the drug |
Listed now, available (4)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Available; Demand increase for the drug |
| Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3) | XGen Pharmaceuticals DJB, Inc. | Current posted November 21, 2023, updated September 22, 2026 | Available |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35) | Hikma Pharmaceuticals USA, Inc. | Current posted November 21, 2023, updated September 18, 2026 | Available |
| Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6) | XGen Pharmaceuticals DJB, Inc. | Current posted November 21, 2023, updated September 22, 2026 | Unvailable; Demand increase for the drug |
Source: FDA Drug Shortage Database via openFDA, read October 8, 2026
What next?
- Every shortage now
- medicines by presentations in shortage