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FDA Drug Shortage Database

Lorazepam (Ativan) shortage

The FDA Drug Shortage Database lists 10 of 11 lorazepam presentations as limited or unavailable (updated October 5, 2026); the first entry was posted on May 3, 2018. 1 more presentation is on the list as available.

  • Generic listed
  • In shortage
  • Boxed warning
  • DEA Schedule IV

Check it at the source: the FDA Drug Shortage Database.

Which strengths are short?

StrengthLimited or unavailable nowListed now, availableResolved or discontinued
2mg/1ml injection610
4mg/1ml injection400

Which presentations are listed?

Limited or unavailable now (10)

PresentationCompanyStatus and datesAvailability and reason given
Ativan, Injection, 2 mg/1 mL (NDC 0641-6000-10)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Unavailable; Other
Ativan, Injection, 2 mg/1 mL (NDC 0641-6001-25)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Limited Availability; Demand increase for the drug
Ativan, Injection, 4 mg/1 mL (NDC 0641-6002-10)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Unavailable; Other
Ativan, Injection, 4 mg/1 mL (NDC 0641-6003-25)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Unavailable; Other
Lorazepam, Injection, 2 mg/1 mL (NDC 0641-6044-25)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Limited Availability; Demand increase for the drug
Lorazepam, Injection, 2 mg/1 mL (NDC 0641-6046-10)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Unavailable; Other
Lorazepam, Injection, 2 mg/1 mL (NDC 65219-368-02)Fresenius Kabi USA, LLCCurrent posted May 3, 2018, updated September 15, 2026Unavailable; Demand increase for the drug
Lorazepam, Injection, 2 mg/1 mL Syringes (NDC 0409-1985-30)Hospira, Inc., a Pfizer CompanyCurrent posted May 3, 2018, updated September 22, 2026Limited Availability; Demand increase for the drug
Lorazepam, Injection, 4 mg/1 mL (NDC 0641-6045-25)Hikma Pharmaceuticals USA, Inc.Current posted September 5, 2018, updated September 18, 2026Unavailable; Other
Lorazepam, Injection, 4 mg/1 mL (NDC 0641-6047-10)Hikma Pharmaceuticals USA, Inc.Current posted May 3, 2018, updated September 18, 2026Unavailable; Other

Listed now, available (1)

PresentationCompanyStatus and datesAvailability and reason given
Lorazepam, Injection, 2 mg/1 mL (NDC 76329-8261-1)Amphastar Pharmaceuticals, Inc.Current posted May 3, 2018, updated October 5, 2026Available

Source: FDA Drug Shortage Database via openFDA, read October 8, 2026

Are medicines for the same conditions short too?

Medicines whose labels share an indication with this one, and their own shortage status; listed as records, not substitutes.

MedicineShared indicationShortageGeneric labelersPharmacy cost
ClonazepamAnxietyIn shortage31 labelers$0.0244 per tablet 1 mg tablet
AlprazolamAnxietyNo current entry30 labelers$0.0236 per tablet 0.25 mg tablet
DiazepamAnxietyNo current entry45 labelers$0.0283 per tablet 10 mg tablet
ChlordiazepoxideAnxietyNo current entry15 labelers$0.158 per capsule 25 mg capsule
ClorazepateAnxietyNo current entry8 labelers$0.524 per tablet 3.75 mg tablet
OxazepamAnxietyNo current entry6 labelers$0.725 per capsule 10 mg capsule
Amitriptyline and chlordiazepoxideAnxietyNo current entry1 labeler$1.20 per unit 5-12.5
BuspironeAnxietyNo current entry47 labelers$0.043 per tablet 15 mg tablet
HydroxyzineAnxietyNo current entry61 labelers$0.0326 per tablet 25 mg tablet
MeprobamateAnxietyNo current entry3 labelers$5.89 per tablet 400 mg tablet
Amitriptyline and perphenazineAnxietyNo current entry1 labelern/a

Source: FDA drug labels, FDA Drug Shortage Database, NDC Directory, CMS NADAC of October 7, 2026 (FDA files October 8, 2026)

What next?

Every shortage now
medicines by presentations in shortage