DEA controlled substances
Schedule III drugs
20 medicines are listed in FDA's NDC Directory with DEA schedule III; 17 are listed from generic labelers (directory read October 8, 2026).
Which medicines are schedule III?
The schedule is the one listed on the products; the DEA's own schedules decide the law.
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Testosterone | Jatenzo, Xyosted, Kyzatrex | 33 labelers | $11.39 per mL 200 mg/mL | No | No current entry | 70 |
| Buprenorphine | Belbuca, Brixadi, Butrans | 27 labelers | $0.277 per tablet 2 mg tablet sl | No | No current entry | 12 |
| Buprenorphine and naloxone | Zubsolv, Suboxone | 26 labelers | $0.521 per tablet 2-0.5 mg sl tablet | No | No current entry | 2 |
| Acetaminophen and codeine | none listed | 24 labelers | $0.256 per tablet 3 tablet | Yes | No current entry | 5 |
| Acetaminophen and butalbital and caffeine | Fioricet, Butal | 35 labelers | $0.122 per tablet 50-325-40 mg tablet | Yes | No current entry | 2 |
| Perampanel | Fycompa | 3 labelers | $14.43 per tablet 4 mg tablet | Yes | No current entry | 1 |
| Ketamine | Ketalar | 10 labelers | $0.556 per mL 500 mg/10 mL vial | No | A presentation being discontinued | 9 |
| Phendimetrazine | none listed | 11 labelers | $0.132 per tablet 35 mg tablet | No | No current entry | 0 |
| Dronabinol | Marinol, Syndros | 1 labeler | $3.35 per capsule 5 mg capsule | No | No current entry | 0 |
| Acetaminophen and butalbital | Allzital, Tencon | 10 labelers | $0.571 per tablet 50-325 mg tablet | Yes | No current entry | 0 |
| Sodium oxybate | Lumryz, Xyrem | 3 labelers | n/a | Yes | A presentation being discontinued | 0 |
| Acetaminophen, butalbital, caffeine and codeine | none listed | 5 labelers | $0.798 per capsule 50-325-40-30 mg capsule | Yes | No current entry | 0 |
| Benzphetamine | none listed | 6 labelers | n/a | No | No current entry | 2 |
| Aspirin and butalbital and caffeine | none listed | 5 labelers | $0.948 per capsule 50-325-40 mg capsule | No | No current entry | 0 |
| Aspirin, butalbital, caffeine and codeine | none listed | 4 labelers | $1.00 per capsule Ascomp with codeine capsule | Yes | No current entry | 0 |
| Methyltestosterone | Methitest | 2 labelers | n/a | No | No current entry | 0 |
| Acetaminophen and caffeine and dihydrocodeine | Trezix | 1 labeler | n/a | Yes | No current entry | 0 |
| Calcium oxybate, magnesium oxybate, potassium oxybate and sodium oxybate | Xywav | none listed | n/a | Yes | No current entry | 0 |
| Chlorpheniramine and codeine | Tuxarin | none listed | n/a | Yes | No current entry | 0 |
| Esketamine | Spravato | none listed | $429.98 per unit 84 mg dose pack | Yes | No current entry | 0 |
Source: FDA NDC Directory (DEA schedule field) via openFDA, October 8, 2026; the DEA schedules