What the FDA labels say about taking them together
Triazolam and voriconazole
Voriconazole's FDA label of February 26, 2026 names triazolam in its drug interactions section; the triazolam label PlainMeds reads does not name voriconazole. The voriconazole label: “Drug/Drug Class: Other benzodiazepines including triazolam and alprazolam (CYP3A4 Inhibition); Drug Plasma Exposure (C max and AUC τ): In Vitro Studies Demonstrated Potential for Voriconazole to Inhibit Metabolism; …”
Check it at the source: the triazolam FDA label on DailyMed (effective July 10, 2026, Mylan Pharmaceuticals Inc.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the triazolam label say about voriconazole?
Triazolam's label (effective July 10, 2026) does not name voriconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Triazolam), NDA017892 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective July 10, 2026 (SPL set 5add318e-11b9-42f8-b052-0d8cebb32fcf), via openFDA; the full label on DailyMed
What does the voriconazole label say about triazolam?
Voriconazole label, drug interactionsDrug/Drug Class (Mechanism of Interaction by Voriconazole): Other benzodiazepines including triazolam and alprazolam (CYP3A4 Inhibition); Drug Plasma Exposure (C max and AUC τ): In Vitro Studies Demonstrated Potential for Voriconazole to Inhibit Metabolism (Increased Plasma Exposure); Prevention or Management Recommendations: Refer to drug-specific labeling for details.
Voriconazole label (Xellia Pharmaceuticals USA LLC, January 11, 2023), drug interactionsDrug/Drug Class (Mechanism of Interaction by Voriconazole): Other benzodiazepines including triazolam and alprazolam (CYP3A4 Inhibition); Drug Plasma Exposure (C max and AUC τ): In Vitro Studies Demonstrated Potential for Voriconazole to Inhibit Metabolism (Increased Plasma Exposure); Recommendations for Drug Dosage Adjustment/Comments: Refer to drug-specific labeling for details.
Source: FDA drug label (Voriconazole, NDA208562), Xellia Pharmaceuticals USA LLC, effective January 11, 2023 (SPL set 9ec6eda2-2f15-423b-9ec6-819379a426e1), via openFDA
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Triazolam | Voriconazole | |
|---|---|---|
| Labeled for | Insomnia | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.308 per tablet 0.25 mg tablet | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once