What the FDA labels say about taking them together
Ibuprofen and voriconazole
Voriconazole's FDA label of February 26, 2026 names ibuprofen in its drug interactions section; the ibuprofen labels PlainMeds reads (2) do not name voriconazole. The voriconazole label: “NSAIDs Non-Steroidal Anti-Inflammatory Drug including. ibuprofen and diclofenac (CYP2C9 Inhibition) Increased Frequent monitoring for adverse reactions and toxicity related to NSAIDs.”
Check it at the source: the ibuprofen FDA label on DailyMed (effective January 1, 2026, Savings Distributors LLC); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the ibuprofen label say about voriconazole?
Ibuprofen's label (effective January 1, 2026) and its 1 other brand-application label do not name voriconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Motrin IB), NDA019012 (Kenvue Brands), as published by Savings Distributors LLC, effective January 1, 2026 (SPL set 56846774-8413-c306-e063-6394a90a2be8), via openFDA; the full label on DailyMed
What does the voriconazole label say about ibuprofen?
Voriconazole label, drug interactionsNSAIDs Non-Steroidal Anti-Inflammatory Drug including. ibuprofen and diclofenac (CYP2C9 Inhibition) Increased Frequent monitoring for adverse reactions and toxicity related to NSAIDs.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ibuprofen | Voriconazole | |
|---|---|---|
| Labeled for | Fever, Osteoarthritis, Rheumatoid arthritis, Pain, Cough and cold | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0573 per tablet 800 mg tablet | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once