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What the FDA labels say about taking them together

Voclosporin and voriconazole

Voriconazole's FDA label of February 26, 2026 names voclosporin in its contraindications section; the voclosporin label PlainMeds reads does not name voriconazole. The voriconazole label: “Contraindicated”

Check it at the source: the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).

What does the voclosporin label say about voriconazole?

Voclosporin's label (effective August 25, 2026) does not name voriconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed

What does the voriconazole label say about voclosporin?

Voriconazole label, contraindications

Voclosporin 2.

Voriconazole label, drug interactions

Drug/Drug Class (Mechanism of Interaction by Voriconazole): Voclosporin (CYP3A4 Inhibition); Drug Plasma Exposure (C max and AUC τ): Not Studied In Vivo or In Vitro, but Voriconazole is Likely to Significantly Increase the Plasma Concentrations of Voclosporin; Prevention or Management Recommendations: Contraindicated

Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Voclosporin generic labelers
31Voriconazole generic labelers
VoclosporinVoriconazole
Labeled forn/aFungal infections
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$1.88 per tablet 200 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?