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What the FDA labels say about taking them together

Verapamil and voclosporin

Voclosporin's FDA label of August 25, 2026 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name voclosporin. The voclosporin label: “Reduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors.”

Check it at the source: the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).

What does the verapamil label say about voclosporin?

Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

What does the voclosporin label say about verapamil?

Voclosporin label, drug interactions

Reduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors (e.g., verapamil, fluconazole, diltiazem) [see Dosage and Administration ( 2.5 ].

Voclosporin label, warnings and precautions

Certain calcium-channel blocking agents (verapamil and diltiazem) may increase voclosporin blood concentrations and require dosage reduction of LUPKYNIS [see Dosage and Administration ( 2.5 ) and Drug Interactions ( 7.2 )].

Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

43Verapamil generic labelers
0Voclosporin generic labelers
VerapamilVoclosporin
Labeled forHigh blood pressure, Atrial fibrillation, Anginan/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.191 per tablet 180 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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