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What the FDA labels say about taking them together

Venetoclax and warfarin

Venetoclax's FDA label of May 20, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name venetoclax. The venetoclax label: “Concomitant use of VENCLEXTA increases warfarin C max and AUC 0-INF, which may increase the risk of bleeding.”

Check it at the source: the venetoclax FDA label on DailyMed (effective May 20, 2026, AbbVie Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the venetoclax label say about warfarin?

Venetoclax label, drug interactions

Concomitant use of VENCLEXTA increases warfarin C max and AUC 0-INF [see Clinical Pharmacology ( 12.3 )], which may increase the risk of bleeding.

Source: FDA drug label (Venclexta), AbbVie Inc., effective May 20, 2026 (SPL set b118a40d-6b56-cee3-10f6-ded821a97018), via openFDA; the full label on DailyMed

What does the warfarin label say about venetoclax?

Warfarin's label (effective May 29, 2026) does not name venetoclax in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Venetoclax generic labelers
19Warfarin generic labelers
VenetoclaxWarfarin
Labeled forLeukemia, lymphoma and myelomaBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?