What the FDA labels say about taking them together
Vasopressin and vincristine
Vasopressin's FDA label of February 21, 2025 names vincristine in its drug interactions section; the vincristine label PlainMeds reads does not name vasopressin. The vasopressin label: “Suspected of Causing SIADH Use with drugs suspected of causing SIADH may increase the pressor effect in addition to the antidiuretic effect of Vasostrict ®.”
Check it at the source: the vasopressin FDA label on DailyMed (effective February 21, 2025, Baxter Healthcare Corporation); the vincristine FDA label on DailyMed (effective February 17, 2026, Hospira, Inc.).
What does the vasopressin label say about vincristine?
Vasopressin label, drug interactionsSuspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasopressin in Sodium Chloride Injection.
Source: FDA drug label (Vasostrict, NDA204485), Par Health USA, LLC, effective April 21, 2026 (SPL set b1147beb-743e-4c62-8927-91192447f8b8), via openFDA
Source: FDA drug label (Vasopressin, NDA212593), American Regent, Inc., effective October 31, 2024 (SPL set 0ab267f4-9ec9-44fd-8521-f975074667d9), via openFDA
Source: FDA drug label (Vasopressin in 0.9% Sodium Chloride), Baxter Healthcare Corporation, effective February 21, 2025 (SPL set b5b2c367-6b7e-40be-a296-c4632f3e783f), via openFDA; the full label on DailyMed
What does the vincristine label say about vasopressin?
Vincristine's label (effective February 17, 2026) does not name vasopressin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VinCRIStine Sulfate), Hospira, Inc., effective February 17, 2026 (SPL set b22e4c8e-dbe1-4d4b-a026-e1812974071c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Vasopressin | Vincristine | |
|---|---|---|
| Labeled for | n/a | Leukemia, lymphoma and myeloma |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once