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What the FDA labels say about taking them together

Felbamate and vasopressin

Vasopressin's FDA label of February 21, 2025 names felbamate in its drug interactions section; the felbamate label PlainMeds reads does not name vasopressin. The vasopressin label: “Suspected of Causing SIADH Use with drugs suspected of causing SIADH may increase the pressor effect in addition to the antidiuretic effect of Vasostrict ®.”

Check it at the source: the felbamate FDA label on DailyMed (effective August 15, 2025, Viatris Specialty LLC); the vasopressin FDA label on DailyMed (effective February 21, 2025, Baxter Healthcare Corporation).

What does the felbamate label say about vasopressin?

Felbamate's label (effective August 15, 2025) does not name vasopressin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Felbatol), NDA020189 (Mylan Speciality Lp), as published by Viatris Specialty LLC, effective August 15, 2025 (SPL set 2f522701-397a-11de-8a39-0800200c9a66), via openFDA; the full label on DailyMed

What does the vasopressin label say about felbamate?

Vasopressin label, drug interactions

Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasopressin in Sodium Chloride Injection.

Source: FDA drug label (Vasostrict, NDA204485), Par Health USA, LLC, effective April 21, 2026 (SPL set b1147beb-743e-4c62-8927-91192447f8b8), via openFDA

Source: FDA drug label (Vasopressin, NDA212593), American Regent, Inc., effective October 31, 2024 (SPL set 0ab267f4-9ec9-44fd-8521-f975074667d9), via openFDA

Source: FDA drug label (Vasopressin in 0.9% Sodium Chloride), Baxter Healthcare Corporation, effective February 21, 2025 (SPL set b5b2c367-6b7e-40be-a296-c4632f3e783f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Felbamate generic labelers
10Vasopressin generic labelers
FelbamateVasopressin
Labeled forSeizures and epilepsyn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$1.00 per tablet 600 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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