What the FDA labels say about taking them together
Lithium and valsartan
Valsartan's FDA label of August 5, 2026 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name valsartan. The valsartan label: “Increases in serum lithium level and lithium toxicity”
Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the valsartan FDA label on DailyMed (effective August 5, 2026, Macleods Pharmaceuticals Limited).
What does the lithium label say about valsartan?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name valsartan in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
What does the valsartan label say about lithium?
Valsartan label, drug interactionsIncreases in serum lithium level and lithium toxicity
Diovan label (Novartis Pharmaceuticals Corporation, August 11, 2026), drug interactionsIncreased risk of renal impairment, hypotension, and hyperkalemia ( 7.3 ) Lithium: Increases in serum lithium level and lithium toxicity
Source: FDA drug label (Diovan, NDA021283), Novartis Pharmaceuticals Corporation, effective August 11, 2026 (SPL set 5ddba454-f3e6-43c2-a7a6-58365d297213), via openFDA
Source: FDA drug label (Valsartan), Macleods Pharmaceuticals Limited, effective August 5, 2026 (SPL set 251ccff4-bf86-453b-9d1c-e3c1ecfd3a46), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lithium | Valsartan | |
|---|---|---|
| Labeled for | Bipolar disorder | High blood pressure, Heart failure |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.104 per capsule 300 mg capsule | $0.0963 per tablet 40 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once