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What the FDA labels say about taking them together

Amphotericin b and valganciclovir

Valganciclovir's FDA label of December 8, 2025 names amphotericin b in its drug interactions section; the amphotericin b label PlainMeds reads does not name valganciclovir. The valganciclovir label: “Monitor renal function when VALCYTE is coadministered with cyclosporine or amphotericin B because of potential increase in serum creatinine.”

Check it at the source: the amphotericin b FDA label on DailyMed (effective June 3, 2025, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the valganciclovir FDA label on DailyMed (effective December 8, 2025, H2-Pharma, LLC).

What does the amphotericin b label say about valganciclovir?

Amphotericin b's label (effective June 3, 2025) does not name valganciclovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amphotericin B), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective June 3, 2025 (SPL set 2b2f3ff5-9d62-4ad2-8eac-1181e5911513), via openFDA; the full label on DailyMed

What does the valganciclovir label say about amphotericin b?

Valganciclovir label, drug interactions

Name of the Concomitant Drug: Cyclosporine or amphotericin B; Change in the Concentration of Ganciclovir or Concomitant Drug: Unknown; Clinical Comment: Monitor renal function when VALCYTE is coadministered with cyclosporine or amphotericin B because of potential increase in serum creatinine [see ].

Source: FDA drug label (Valcyte), NDA021304 (Cheplapharm), as published by H2-Pharma, LLC, effective December 8, 2025 (SPL set 4c517a39-2ded-4c5a-8d56-276853414b31), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Amphotericin b generic labelers
19Valganciclovir generic labelers
Amphotericin bValganciclovir
Labeled forFungal infectionsn/a
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$1.91 per tablet 450 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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