What the FDA labels say about taking them together
Trabectedin and voriconazole
Trabectedin's FDA label (Yondelis) of January 6, 2026 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name trabectedin. The trabectedin label: “Avoid using strong CYP3A inhibitors in patients taking YONDELIS.”
Check it at the source: the trabectedin FDA label on DailyMed (effective June 29, 2026, Apotex Corp.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the trabectedin label say about voriconazole?
Yondelis label (Janssen Products, LP, January 6, 2026), drug interactionsAvoid using strong CYP3A inhibitors (e.g., oral ketoconazole, itraconazole, posaconazole, voriconazole, clarithromycin, telithromycin, indinavir, lopinavir, ritonavir, boceprevir, nelfinavir, saquinavir, telaprevir, nefazodone, conivaptan) in patients taking YONDELIS.
Source: FDA drug label (Yondelis, NDA207953), Janssen Products, LP, effective January 6, 2026 (SPL set 472bd78e-be17-4b9d-90f4-9482c3aec9ff), via openFDA
Source: FDA drug label (EVDI), Apotex Corp., effective June 29, 2026 (SPL set c1d50f5c-4202-27f3-4798-a9708114ddea), via openFDA; the full label on DailyMed
What does the voriconazole label say about trabectedin?
Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name trabectedin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Trabectedin | Voriconazole | |
|---|---|---|
| Labeled for | n/a | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once