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What the FDA labels say about taking them together

Ethacrynic acid and torsemide

Torsemide's FDA label of May 8, 2024 names ethacrynic acid in its drug interactions section; the ethacrynic acid label PlainMeds reads does not name torsemide. The torsemide label: “Loop diuretics increase the ototoxic potential of other ototoxic drugs, including aminoglycoside antibiotics and ethacrynic acid.”

Check it at the source: the ethacrynic acid FDA label on DailyMed (effective August 31, 2020, Bausch Health US, LLC); the torsemide FDA label on DailyMed (effective May 8, 2024, Aurobindo Pharma Limited).

What does the ethacrynic acid label say about torsemide?

Ethacrynic acid's label (effective August 31, 2020) does not name torsemide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (EDECRIN), Bausch Health US, LLC, effective August 31, 2020 (SPL set 1efe378e-fee1-4ae9-8ea5-0fe2265fe2d8), via openFDA; the full label on DailyMed

What does the torsemide label say about ethacrynic acid?

Torsemide label, drug interactions

Loop diuretics increase the ototoxic potential of other ototoxic drugs, including aminoglycoside antibiotics and ethacrynic acid.

Source: FDA drug label (Torsemide), Aurobindo Pharma Limited, effective May 8, 2024 (SPL set 55e88727-864e-4313-860c-31a6ca45168f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Ethacrynic acid generic labelers
20Torsemide generic labelers
Ethacrynic acidTorsemide
Labeled forEdema (fluid retention), Heart failureHigh blood pressure, Heart failure
Boxed warningNoNo
Pharmacy cost (NADAC)$0.807 per tablet 25 mg tablet$0.0636 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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