What the FDA labels say about taking them together
Toremifene and voriconazole
Toremifene's FDA label of November 13, 2024 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name toremifene. The toremifene label: “The administration of FARESTON with agents that are strong CYP3A4 inhibitors increase the steady-state concentration in serum and should be avoided.”
Check it at the source: the toremifene FDA label on DailyMed (effective November 13, 2024, Kyowa Kirin, Inc.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the toremifene label say about voriconazole?
Toremifene label, drug interactionsThe administration of FARESTON with agents that are strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, atazanavir, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, and voriconazole) increase the steady-state concentration in serum and should be avoided.
Source: FDA drug label (Fareston), Kyowa Kirin, Inc., effective November 13, 2024 (SPL set 2cab8dd1-3a10-48e6-86ce-0e5275ed49e5), via openFDA; the full label on DailyMed
What does the voriconazole label say about toremifene?
Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name toremifene in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Toremifene | Voriconazole | |
|---|---|---|
| Labeled for | Breast cancer | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $19.60 per tablet 60 mg tablet | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once