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What the FDA labels say about taking them together

Testosterone and warfarin

Testosterone's FDA label (Jatenzo) of September 30, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name testosterone. The testosterone label: “More frequent monitoring of International Normalized Ratio (INR) and prothrombin time is recommended in patients taking warfarin.”

Check it at the source: the testosterone FDA label on DailyMed (effective July 25, 2025, Azurity Pharmaceuticals, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the testosterone label say about warfarin?

Jatenzo label (TOLMAR Inc., September 30, 2025), drug interactions

More frequent monitoring of International Normalized Ratio (INR) and prothrombin time is recommended in patients taking warfarin ( 7.2 ).

Vogelxo label (Upsher-Smith Laboratories, LLC, July 14, 2025), drug interactions

More frequent monitoring of International Normalized Ratio (INR) and prothrombin time is recommended in patients taking warfarin. ( 7.2 ) Use of testosterone with corticosteroids may result in increased fluid retention.

Source: FDA drug label (Jatenzo, NDA206089), TOLMAR Inc., effective September 30, 2025 (SPL set ed7b5d41-7475-4c10-99b9-b62b3434ae60), via openFDA

Source: FDA drug label (Vogelxo, NDA204399), Upsher-Smith Laboratories, LLC, effective July 14, 2025 (SPL set 2dd150f6-cdfd-4d51-8888-12b288f26262), via openFDA

Source: FDA drug label (AZMIRO), Azurity Pharmaceuticals, Inc., effective July 25, 2025 (SPL set 235b5625-570d-3fba-e063-6394a90aa2d1), via openFDA; the full label on DailyMed

What does the warfarin label say about testosterone?

Warfarin's label (effective May 29, 2026) does not name testosterone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

33Testosterone generic labelers
19Warfarin generic labelers
TestosteroneWarfarin
Labeled forBreast cancerBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$11.39 per mL 200 mg/mL$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?