Cimetidine · more major-labeled pairs than Terbinafine
SPL labels Terbinafine + Cimetidine as minor; Terbinafine 16 / Cimetidine 63 in that band.
Mechanism on file: Cimetidine slows down the process of removing terbinafine from your body by blocking certain liver enzymes.
FDA SPL severity: Minor
Terbinafine + Cimetidine · SPL mechanism field
Cimetidine slows down the process of removing terbinafine from your body by blocking certain liver enzymes.
Minor band excerpt · Terbinafine with Cimetidine
Drug interactions have also been noted with cimetidine, fluconazole, cyclosporine, rifampin, and caffeine. Terbinafine clearance is increased 100% by rifampin, a CYP450 enzyme inducer, and decreased 33% by cimetidine, a CYP450 enzyme inhibitor.
Terbinafine · 16 minor + 17 total pairs
- Amiodarone minor
- Clozapine minor
- Cyclosporine minor
- Desipramine minor
Cimetidine · 4 major-labeled pairs (vs Terbinafine's 0)
- Albendazole minor
- Alogliptin minor
- Alosetron minor
- Alprazolam minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.