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What the FDA labels say about taking them together

Talazoparib and verapamil

Talazoparib's FDA label of April 10, 2026 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name talazoparib. The talazoparib label: “Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.”

Check it at the source: the talazoparib FDA label on DailyMed (effective April 10, 2026, Pfizer Laboratories Div Pfizer Inc); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).

What does the talazoparib label say about verapamil?

Talazoparib label, drug interactions

Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.

Source: FDA drug label (Talzenna), Pfizer Laboratories Div Pfizer Inc, effective April 10, 2026 (SPL set c6fd147f-a77e-4a0b-9280-e82ecc41b4be), via openFDA; the full label on DailyMed

What does the verapamil label say about talazoparib?

Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name talazoparib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Talazoparib generic labelers
43Verapamil generic labelers
TalazoparibVerapamil
Labeled forBreast cancer, Prostate cancerHigh blood pressure, Atrial fibrillation, Angina
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.191 per tablet 180 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?