What the FDA labels say about taking them together
Sotalol and verapamil
Sotalol's FDA label of December 16, 2024 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name sotalol. The sotalol label: “Digitalis glycosides, diltiazem, verapamil, and beta-blockers slow atrioventricular conduction and decrease heart rate.”
Check it at the source: the sotalol FDA label on DailyMed (effective December 16, 2024, Legacy Pharma USA, Inc.); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the sotalol label say about verapamil?
Sotalol label, drug interactionsDigitalis glycosides, diltiazem, verapamil, and beta-blockers slow atrioventricular conduction and decrease heart rate.
Source: FDA drug label (BETAPACE), Legacy Pharma USA, Inc., effective December 16, 2024 (SPL set a6a7702f-36c9-45db-b640-453dc324baee), via openFDA; the full label on DailyMed
What does the verapamil label say about sotalol?
Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name sotalol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Sotalol | Verapamil | |
|---|---|---|
| Labeled for | Atrial fibrillation | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0707 per tablet 80 mg tablet | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once