What the FDA labels say about taking them together
Silodosin and verapamil
Silodosin's FDA label of April 15, 2026 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name silodosin. The silodosin label: “Concomitant administration with moderate CYP3A4 inhibitors may increase concentration of silodosin.”
Check it at the source: the silodosin FDA label on DailyMed (effective April 15, 2026, Amneal Pharmaceuticals NY LLC); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the silodosin label say about verapamil?
Silodosin label, drug interactionsConcomitant administration with moderate CYP3A4 inhibitors (e.g., diltiazem, erythromycin, verapamil) may increase concentration of silodosin.
Source: FDA drug label (Silodosin), Amneal Pharmaceuticals NY LLC, effective April 15, 2026 (SPL set de619e27-9384-4b86-abdc-de0557cd39e8), via openFDA; the full label on DailyMed
What does the verapamil label say about silodosin?
Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name silodosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Silodosin | Verapamil | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH) | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.319 per capsule 8 mg capsule | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once