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What the FDA labels say about taking them together

Ritonavir and timolol

Ritonavir's FDA label of July 23, 2026 names timolol in its drug interactions section; the timolol labels PlainMeds reads (4) do not name ritonavir. The ritonavir label: “Caution is warranted and clinical monitoring of patients is recommended. A dose decrease may be needed for these drugs when co-administered with ritonavir.”

Check it at the source: the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.); the timolol FDA label on DailyMed (effective June 27, 2025, Thea Pharma Inc.).

What does the ritonavir label say about timolol?

Ritonavir label, drug interactions

Concomitant Drug Class/Drug Name: β-Blockers: metoprolol, timolol; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ beta-blockers; Clinical Comment: Caution is warranted and clinical monitoring of patients is recommended. A dose decrease may be needed for these drugs when co-administered with ritonavir.

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

What does the timolol label say about ritonavir?

Timolol's label (effective June 27, 2025) and its 3 other brand-application labels do not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (BETIMOL), Thea Pharma Inc., effective June 27, 2025 (SPL set 3ae775f4-340c-4bf4-aa49-8a31daba0f8b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

7Ritonavir generic labelers
22Timolol generic labelers
RitonavirTimolol
Labeled forHIVGlaucoma, High blood pressure, Migraine
Boxed warningYesNo
Pharmacy cost (NADAC)$0.607 per tablet 100 mg tablet$0.774 per mL 0.5% eye drops
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?