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What the FDA labels say about taking them together

Ritonavir and thioridazine

Ritonavir's FDA label of July 23, 2026 names thioridazine in its drug interactions section; the thioridazine label PlainMeds reads does not name ritonavir. The ritonavir label: “A dose decrease may be needed for these drugs when co-administered with ritonavir.”

Check it at the source: the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.); the thioridazine FDA label on DailyMed (effective November 11, 2025, Mylan Institutional Inc.).

What does the ritonavir label say about thioridazine?

Ritonavir label, drug interactions

Concomitant Drug Class/Drug Name: Antipsychotics: perphenazine, risperidone, thioridazine; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ antipsychotics; Clinical Comment: A dose decrease may be needed for these drugs when co-administered with ritonavir.

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

What does the thioridazine label say about ritonavir?

Thioridazine's label (effective November 11, 2025) does not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Thioridazine Hydrochloride), Mylan Institutional Inc., effective November 11, 2025 (SPL set 52fea941-0b47-41c1-b00d-f88150e8ab93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

7Ritonavir generic labelers
5Thioridazine generic labelers
RitonavirThioridazine
Labeled forHIVn/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.607 per tablet 100 mg tablet$0.571 per tablet 25 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?