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What the FDA labels say about taking them together

Quinidine and sertraline

Sertraline's FDA label of August 8, 2023 names quinidine in its drug interactions section; the quinidine label PlainMeds reads does not name sertraline.

Check it at the source: the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.); the sertraline FDA label on DailyMed (effective August 8, 2023, Viatris Specialty LLC).

What does the quinidine label say about sertraline?

Quinidine's label (effective February 1, 2018) does not name sertraline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed

What does the sertraline label say about quinidine?

Sertraline label, drug interactions

Class 1A antiarrhythmic medications (e.g., quinidine, procainamide);

Source: FDA drug label (Zoloft), Viatris Specialty LLC, effective August 8, 2023 (SPL set fda754f6-d0f3-4dce-a17a-927d64f912f7), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Quinidine generic labelers
47Sertraline generic labelers
QuinidineSertraline
Labeled forAtrial fibrillationDepression, Anxiety
Boxed warningYesYes
Pharmacy cost (NADAC)$4.92 per tablet 324 mg tablet$0.0507 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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