What the FDA labels say about taking them together
Probenecid and seladelpar lysine
Seladelpar lysine's FDA label of February 3, 2026 names probenecid in its drug interactions section; the probenecid label PlainMeds reads does not name seladelpar lysine. The seladelpar lysine label: “DRUG INTERACTIONS Probenecid: Avoid concomitant use. Strong CYP2C9 Inhibitors: Monitor for adverse effects. Dual Moderate CYP2C9 and Moderate to Strong CYP3A4 Inhibitors:”
Check it at the source: the probenecid FDA label on DailyMed (effective January 5, 2021, Lannett Company, Inc.); the seladelpar lysine FDA label on DailyMed (effective February 3, 2026, Gilead Sciences, Inc).
What does the probenecid label say about seladelpar lysine?
Probenecid's label (effective January 5, 2021) does not name seladelpar lysine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Probenecid), Lannett Company, Inc., effective January 5, 2021 (SPL set ab497fd8-00c3-4364-b003-b39d21fbdf38), via openFDA; the full label on DailyMed
What does the seladelpar lysine label say about probenecid?
Seladelpar lysine label, drug interactionsDRUG INTERACTIONS Probenecid: Avoid concomitant use. ( 7.1 ) Strong CYP2C9 Inhibitors: Monitor for adverse effects. ( 7.1 ) Dual Moderate CYP2C9 and Moderate to Strong CYP3A4 Inhibitors:
Source: FDA drug label (Livdelzi), Gilead Sciences, Inc, effective February 3, 2026 (SPL set 89f79d98-135c-40b2-a585-6996c04e599c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Probenecid | Seladelpar lysine | |
|---|---|---|
| Labeled for | Gout | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.636 per tablet 500 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once