What the FDA labels say about taking them together
Digoxin and prasugrel
Prasugrel's FDA label of February 11, 2025 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name prasugrel.
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the prasugrel FDA label on DailyMed (effective February 11, 2025, Panacea Biotec Limited).
What does the digoxin label say about prasugrel?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name prasugrel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the prasugrel label say about digoxin?
Prasugrel label, drug interactionsPrasugrel tablets can be administered with aspirin (75 mg to 325 mg per day), heparin, GPIIb/IIIa inhibitors, statins, digoxin, and drugs that elevate gastric pH, including proton pump inhibitors and H 2 blockers [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Effient, NDA022307), Cosette Pharmaceuticals, Inc., effective September 7, 2022 (SPL set 69ea2d58-5353-4222-b61f-cab976fa7e5e), via openFDA
Source: FDA drug label (PRASUGREL), Panacea Biotec Limited, effective February 11, 2025 (SPL set 944c195a-de24-a44c-8baa-84b624b5ddcb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Prasugrel | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | Heart attack and coronary artery disease, Angina |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | $0.263 per tablet 10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once