What the FDA labels say about taking them together
Phenytoin and tinidazole
Tinidazole's FDA label of December 27, 2021 names phenytoin in its drug interactions section; the phenytoin labels PlainMeds reads (2) do not name tinidazole. The tinidazole label: “Monitor for toxicities of these immunosuppressive drugs Fluorouracil: Monitor for fluorouracil-associated toxicities Phenytoin, fosphenytoin:”
Check it at the source: the phenytoin FDA label on DailyMed (effective October 15, 2024, Mylan Pharmaceuticals Inc.); the tinidazole FDA label on DailyMed (effective December 27, 2021, Mission Pharmacal Company).
What does the phenytoin label say about tinidazole?
Phenytoin's label (effective October 15, 2024) and its 1 other brand-application label do not name tinidazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Phenytek), Mylan Pharmaceuticals Inc., effective October 15, 2024 (SPL set 0f94c791-8b07-4b41-927e-c9f28bec5f60), via openFDA; the full label on DailyMed
What does the tinidazole label say about phenytoin?
Tinidazole label, drug interactionsMonitor for toxicities of these immunosuppressive drugs ( 7.1 ) Fluorouracil: Monitor for fluorouracil-associated toxicities ( 7.1 ) Phenytoin, fosphenytoin:
Source: FDA drug label (Tindamax), Mission Pharmacal Company, effective December 27, 2021 (SPL set a0d01539-8413-4703-94cc-d221918630a1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Phenytoin | Tinidazole | |
|---|---|---|
| Labeled for | Seizures and epilepsy | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.145 per capsule 100 mg capsule | $2.35 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once