What the FDA labels say about taking them together
Phenelzine and rizatriptan
Rizatriptan's FDA label of January 29, 2026 names phenelzine in its drug interactions section; the phenelzine label PlainMeds reads does not name rizatriptan. The rizatriptan label: “Plasma concentrations of rizatriptan may be increased by drugs that are selective MAO-A inhibitors (e.g., moclobemide) or nonselective MAO inhibitors [type A and B].”
Check it at the source: the phenelzine FDA label on DailyMed (effective June 6, 2025, Parke-Davis Div of Pfizer Inc); the rizatriptan FDA label on DailyMed (effective January 29, 2026).
What does the phenelzine label say about rizatriptan?
Phenelzine's label (effective June 6, 2025) does not name rizatriptan in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nardil), Parke-Davis Div of Pfizer Inc, effective June 6, 2025 (SPL set 513a41d0-37d4-4355-8a6d-a2c643bce6fa), via openFDA; the full label on DailyMed
What does the rizatriptan label say about phenelzine?
Rizatriptan label, drug interactionsPlasma concentrations of rizatriptan may be increased by drugs that are selective MAO-A inhibitors (e.g., moclobemide) or nonselective MAO inhibitors [type A and B] (e.g., isocarboxazid, phenelzine, tranylcypromine, and pargyline).
Source: FDA drug label (MAXALT), Organon LLC, effective January 29, 2026 (SPL set 007b4644-e0e7-4863-9ae3-fe09676b3f5f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Phenelzine | Rizatriptan | |
|---|---|---|
| Labeled for | n/a | Migraine |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.586 per tablet 15 mg tablet | $0.335 per tablet 10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once