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What the FDA labels say about taking them together

Palbociclib and voriconazole

Palbociclib's FDA label of July 2, 2026 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name palbociclib. The palbociclib label: “Avoid concomitant use of strong CYP3A inhibitors.”

Check it at the source: the palbociclib FDA label on DailyMed (effective July 2, 2026, Pfizer Laboratories Div Pfizer Inc); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).

What does the palbociclib label say about voriconazole?

Palbociclib label, drug interactions

Avoid concomitant use of strong CYP3A inhibitors (e.g., clarithromycin, indinavir, itraconazole, ketoconazole, lopinavir/ritonavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, telithromycin, and voriconazole).

Source: FDA drug label (Ibrance), Pfizer Laboratories Div Pfizer Inc, effective July 2, 2026 (SPL set fecbdd7d-b729-41b5-9872-231b8fe104ce), via openFDA; the full label on DailyMed

What does the voriconazole label say about palbociclib?

Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name palbociclib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Palbociclib generic labelers
31Voriconazole generic labelers
PalbociclibVoriconazole
Labeled forBreast cancerFungal infections
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$1.88 per tablet 200 mg tablet
Shortage nowA presentation being discontinuedA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?