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What the FDA labels say about taking them together

Paclitaxel and verapamil

Verapamil's FDA label (Verapamil Hydrochloride) of November 27, 2024 names paclitaxel in its drug interactions section; the paclitaxel labels PlainMeds reads (4) do not name verapamil. The verapamil label: “Concomitant administration of R verapamil can decrease the clearance of paclitaxel.”

Check it at the source: the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).

What does the paclitaxel label say about verapamil?

Paclitaxel's label (effective January 21, 2026) and its 3 other brand-application labels do not name verapamil in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed

What does the verapamil label say about paclitaxel?

Verapamil Hydrochloride label (Wilshire Pharmaceuticals, Inc., November 27, 2024), drug interactions

Concomitant administration of R verapamil can decrease the clearance of paclitaxel.

Source: FDA drug label (Verapamil Hydrochloride, NDA020943), Wilshire Pharmaceuticals, Inc., effective November 27, 2024 (SPL set 5f665d08-e1e4-422a-88c2-d8834abf9e1a), via openFDA

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

19Paclitaxel generic labelers
43Verapamil generic labelers
PaclitaxelVerapamil
Labeled forBreast cancer, Lung cancerHigh blood pressure, Atrial fibrillation, Angina
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$0.191 per tablet 180 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?