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What the FDA labels say about taking them together

Olodaterol and salmeterol

Olodaterol's FDA label of January 3, 2025 names salmeterol in its warnings and precautions section; the salmeterol label PlainMeds reads does not name olodaterol. The olodaterol label: “A 28-week, placebo-controlled US study comparing the safety of another LABA (salmeterol) with placebo, each added to usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol …”

Check it at the source: the olodaterol FDA label on DailyMed (effective January 3, 2025, Boehringer Ingelheim Pharmaceuticals, Inc.); the salmeterol FDA label on DailyMed (effective October 10, 2022, GlaxoSmithKline LLC).

What does the olodaterol label say about salmeterol?

Olodaterol label, warnings and precautions

A 28-week, placebo-controlled US study comparing the safety of another LABA (salmeterol) with placebo, each added to usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol (13/13,176 in patients treated with salmeterol vs. 3/13,179 in patients treated with placebo;

Source: FDA drug label (Striverdi Respimat), Boehringer Ingelheim Pharmaceuticals, Inc., effective January 3, 2025 (SPL set 5d9a5433-857e-44ea-b3d6-2a400ca0cef5), via openFDA; the full label on DailyMed

What does the salmeterol label say about olodaterol?

Salmeterol's label (effective October 10, 2022) does not name olodaterol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (SEREVENT DISKUS), GlaxoSmithKline LLC, effective October 10, 2022 (SPL set 12d9728e-6b5c-4aee-bfb0-745e542ed2e4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Olodaterol generic labelers
0Salmeterol generic labelers
OlodaterolSalmeterol
Labeled forCOPDAsthma, COPD
Boxed warningNoYes
Pharmacy cost (NADAC)$65.94 per gram Striverdi respimat inhal spray$6.74 per unit 50 mcg
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?