olodaterol
Brand names: Striverdi Respimat
Striverdi Respimat is a medicine that helps people with COPD breathe easier. It contains olodaterol, which is a long-acting beta-2 agonist (LABA).
What it does
Striverdi Respimat is used long-term to treat COPD, including chronic bronchitis and emphysema.
Common side effects
Common cold symptoms, Cough, Back pain
Key warnings
LABAs like olodaterol can raise the risk of asthma-related death if used alone to treat asthma.
How It Works
Olodaterol is a LABA. It works by relaxing the muscles around your airways. This helps to open them up so air can flow in and out of your lungs more easily.
How to Take It
Use Striverdi Respimat exactly as your doctor tells you. Inhale two puffs once a day, at the same time each day. Only use the Striverdi Respimat inhaler to take this medicine. If you haven't used it for over 3 days, spray once to prepare. If you haven't used it for over 21 days, spray until a cloud appears, then repeat 3 more times.
Pregnancy & Breastfeeding
Tell your doctor if you are pregnant or plan to become pregnant. Striverdi Respimat should only be used during pregnancy if the benefit outweighs the risk to the baby. It is not known if Striverdi Respimat passes into breast milk.
Missed Dose
If you miss a dose, take it as soon as you remember. Do not take more than two puffs in 24 hours.
Storage
Store Striverdi Respimat at room temperature, away from freezing temperatures.
Serious Warnings
LABAs like olodaterol can raise the risk of asthma-related death if used alone to treat asthma. Striverdi Respimat is not for asthma. Using too much Striverdi Respimat can cause serious heart problems and may be fatal. If you have a bad reaction, like swelling or trouble breathing, stop using Striverdi Respimat and get medical help right away.
Known Drug Interactions
Avoid administration of STIOLTO RESPIMAT with other anticholinergic-containing drugs. ( 7.6 ) 7.1 Adrenergic Drugs If additional adrenergic drugs are to be administered by any route, they should be used with caution because the sympathetic effects of olodaterol, one component of STIOLTO RESPIMAT, may be potentiated [see Warnings and Precautions (5.3 , 5.6 , 5.10 , 5.11) ] . Although the clinical significance of these effects is not known, caution is advised in the co-administration of STIOLTO RESPIMAT with non-potassium sparing diuretics.
Mechanism: Using two inhalers that contain the same medicine can cause you to have too much of the drug in your system. This can lead to a fast heartbeat, shakiness, or other heart-related problems.
What to do: Avoid using these two medications at the same time. Your doctor should check your prescriptions to make sure you are not using duplicate treatments.
( 7.6 ) 7.1 Adrenergic Drugs If additional adrenergic drugs are to be administered by any route, they should be used with caution because the sympathetic effects of olodaterol, one component of STIOLTO RESPIMAT, may be potentiated [see Warnings and Precautions (5.3 , 5.6 , 5.10 , 5.11) ] . Concomitant treatment with xanthine derivatives, steroids, or diuretics may potentiate any hypokalemic effect of olodaterol [see Warnings and Precautions (5.11) ] . 7.5 Beta-Blockers Beta-adrenergic receptor antagonists (beta-blockers) and the olodaterol component of STIOLTO RESPIMAT may interfere with th...
Mechanism: Using other similar drugs can make the heart and nerve effects of olodaterol much stronger.
What to do: Use these medicines with caution and watch for signs like a fast heartbeat or high blood pressure.
7.7 Inhibitors of Cytochrome P450 and P-gp Efflux Transporter In a drug interaction study using the strong dual CYP and P-gp inhibitor ketoconazole, a 1.7-fold increase of olodaterol maximum plasma concentrations and AUC was observed [see Pharmacokinetics (12.3) ] .
Mechanism: Ketoconazole blocks the natural processes your body uses to break down and remove olodaterol, which causes the drug levels in your blood to rise.
What to do: Your doctor should monitor you for increased side effects since the level of olodaterol in your body may be higher than usual.
Common Questions
Can I use Striverdi Respimat for asthma?
What should I do if Striverdi Respimat doesn't help my breathing right away?
Can I use more than two puffs of Striverdi Respimat a day?
What if I have glaucoma?
What if I have prostate problems?
Can Striverdi Respimat cause heart problems?
What should I do if I have a bad reaction to Striverdi Respimat?
Does Striverdi Respimat have any effect on blood sugar?
Can I use other inhalers with Striverdi Respimat?
How long is Striverdi Respimat good for after I start using the inhaler?
What are the common side effects of olodaterol?
Does olodaterol interact with other medications?
What drug class is olodaterol?
Is olodaterol safe during pregnancy?
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What the FDA Data Shows for olodaterol
The FDA label for olodaterol (sold under brand names such as Striverdi Respimat) classifies it as a prescription-only medication in the Long-Acting Beta-2 Agonist (LABA) class. Striverdi Respimat is used long-term to treat COPD, including chronic bronchitis and emphysema. Official labeling lists 3 commonly reported side effects, including Common cold symptoms, Cough, Back pain.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. The database also lists 3 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated moderate severity. Acquisition-cost data is surveyed weekly by CMS and updated as manufacturers report changes.
Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: June 30, 2025
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- FDA Orange Book — approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed — NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) — post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm — standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files — federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database — current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages