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What the FDA labels say about taking them together

Nitazoxanide and warfarin

Nitazoxanide's FDA label of October 9, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name nitazoxanide. The nitazoxanide label: “… narrow therapeutic indices, as competition for binding sites may occur (e.g., warfarin).”

Check it at the source: the nitazoxanide FDA label on DailyMed (effective October 9, 2025, Rising Pharma Holdings, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the nitazoxanide label say about warfarin?

Nitazoxanide label, drug interactions

Therefore, monitor for adverse reactions when administering nitazoxanide concurrently with other highly plasma protein-bound drugs with narrow therapeutic indices, as competition for binding sites may occur (e.g., warfarin).

Source: FDA drug label (Nitazoxanide), Rising Pharma Holdings, Inc., effective October 9, 2025 (SPL set c0dc0656-3c46-43f9-adea-5285c522cef8), via openFDA; the full label on DailyMed

What does the warfarin label say about nitazoxanide?

Warfarin's label (effective May 29, 2026) does not name nitazoxanide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Nitazoxanide generic labelers
19Warfarin generic labelers
NitazoxanideWarfarin
Labeled forDiarrheaBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$82.20 per tablet 500 mg tablet$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?