What the FDA labels say about taking them together
Nifedipine and verapamil
Nifedipine's FDA label of December 24, 2024 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name nifedipine. The nifedipine label: “Verapamil, a CYP3A inhibitor, can inhibit the metabolism of nifedipine and increase the exposure to nifedipine during concomitant therapy.”
Check it at the source: the nifedipine FDA label on DailyMed (effective December 24, 2024, Aurobindo Pharma Limited); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).
What does the nifedipine label say about verapamil?
Nifedipine label, drug interactionsVerapamil, a CYP3A inhibitor, can inhibit the metabolism of nifedipine and increase the exposure to nifedipine during concomitant therapy.
Source: FDA drug label (Nifedipine), Aurobindo Pharma Limited, effective December 24, 2024 (SPL set eb70b7ff-f9f0-41d0-901a-f4c04ae9ed46), via openFDA; the full label on DailyMed
What does the verapamil label say about nifedipine?
Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name nifedipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nifedipine | Verapamil | |
|---|---|---|
| Labeled for | High blood pressure, Angina | High blood pressure, Atrial fibrillation, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.130 per tablet 30 mg tablet | $0.191 per tablet 180 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once