What the FDA labels say about taking them together
Cimetidine and nicardipine
Nicardipine's FDA label of August 24, 2024 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name nicardipine. The nicardipine label: “Cimetidine increases oral nicardipine plasma levels.”
Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the nicardipine FDA label on DailyMed (effective August 24, 2024, Hikma Pharmaceuticals USA Inc.).
What does the cimetidine label say about nicardipine?
Cimetidine's label (effective July 15, 2026) does not name nicardipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
What does the nicardipine label say about cimetidine?
Nicardipine label, drug interactionsDRUG INTERACTIONS Cimetidine increases nicardipine plasma levels ( 7.3 ). Nicardipine may increase cyclosporine and tacrolimus plasma levels.
Cardene Iv label (Baxter Healthcare Corporation, April 13, 2026), drug interactionsCimetidine increases oral nicardipine plasma levels.
Source: FDA drug label (Cardene Iv, NDA019734), Baxter Healthcare Corporation, effective April 13, 2026 (SPL set a3e33add-0d09-423a-9109-42e5ba7148d5), via openFDA
Source: FDA drug label (Nicardipine Hydrochloride), Hikma Pharmaceuticals USA Inc., effective August 24, 2024 (SPL set 18fb1c2b-0c1e-436c-a5b6-d4840b5da228), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cimetidine | Nicardipine | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | High blood pressure, Angina |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.236 per tablet 300 mg tablet | $1.12 per capsule 20 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once